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Columbus, OH 43213
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adrenoleukodystrophy: Diseases & Medical Conditions Search Results
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adrenoleukodystrophy - Definition: (Source: MedicineNet)

Adrenoleukodystrophy: A rare genetic (inherited) disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. Adrenoleukodystrophy (ALD) is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath of the nerve fibers in the brain. The myelin sheath is a fatty covering which acts as an electrical insulator. ...
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About adrenoleukodystrophy (Source: eMedicineHealth)
A rare genetic (inherited) disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. Adrenoleukodystrophy (ALD) is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath of the nerve fibers in the brain. The myelin sheath is a fatty covering which acts as an electrical insulator. ...
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Causes of adrenoleukodystrophy (Source: MedLinePlus)
Causes Adrenoleukodystrophy is passed down from parents to their children as an X-linked genetic trait . It therefore affects mostly males, although some women who are carriers can have milder forms of the disease. It affects approximately 1 in 20,000 people from all races. The condition results in the buildup of very-long-chain fatty acids in the nervous system, adrenal gland, and testes, which disrupts normal activity. There are three major categories of disease: Childhood cerebral form -- ap ...
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Symptoms of adrenoleukodystrophy (Source: MedLinePlus)
Symptoms Childhood cerebral type: Changes in muscle tone, especially muscle spasms and spasticity; Crossed eyes (strabismus); Decreased understanding of verbal communication (aphasia); Deterioration of handwriting; Difficulty at school; Difficulty understanding spoken material; Hearing loss; Hyperactivity ; Worsening nervous system deterioration Coma; Decreased fine motor control; Paralysis; ; Seizures; Swallowing difficulties; Visual impairment or blindness; Adrenomyelopathy: Difficulty contro ...
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adrenoleukodystrophy - Conventional Treatments (Source: MedLinePlus)
Treatment Adrenal dysfunction is treated with steroids (such as cortisol). A specific treatment for X-linked adrenoleukodystrophy is not available, but eating a diet low in very-long-chain fatty acids and taking special oils can lower the blood levels of very-long-chain fatty acids. These oils are called Lorenzo's oil, after the son of the family who discovered the treatment. This treatment is being tested for X-linked adrenoleukodystrophy, but it does not cure the disease and may not help all ...
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Further Reading on adrenoleukodystrophy
  • Types of Epilepsy ( WebMD )
    An overview of the different types of epilepsy, their symptoms and treatment...such as mental retardation or cerebral palsy. Specific, inherited brain diseases, such as adrenoleukodystrophy (ADL) or...


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