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acromegaly - Definition:
(Source: MedicineNet)
When too much growth hormone is secreted after adolescence, there cannot be an increase in height but acromegaly ensues. The cardinal manifestations of acromegaly include thickening of the skin, soft tissues, and bones of the hands and feet. These effects are insidious and very slowly progressive. Ultimately they cause considerable disability (aside from the need for larger rings, gloves, and shoes) including hoarseness, sleep apnea, joint pain, cardiovascular disease, hypertension, insulin resi
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About acromegaly
(Source:
eMedicineHealth)
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Acromegaly is a serious condition that occurs when the body produces too much of the hormones that control growth. The hormone most often affected is called growth hormone , or GH. It is produced by the pituitary gland , a tiny organ at the base of the brain . ; Growth hormone promotes growth of bone, cartilage , muscle , organs, and other tissues. ; When there is too much growth hormone in the body, these tissues grow larger than normal. This excessive growth can cause serious disease and even
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Causes of acromegaly
(Source: MedLinePlus)
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Causes Acromegaly occurs in about 6 of every 100,000 adults. It is caused by abnormal production of growth hormone after the skeleton and other organs finish growing. Excessive production of growth hormone in children causes gigantism rather than acromegaly. The cause of the increased growth hormone release is usually a noncancerous (benign) tumor of the pituitary gland. The pituitary gland, which is located just below the brain, controls the production and release of several different hormones
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Symptoms of acromegaly
(Source: MedLinePlus)
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Symptoms Body odor; Carpal tunnel syndrome ; Decreased muscle strength ( weakness ); Easy fatigue ; Excessive height (when excess growth hormone production begins in childhood); Excessive sweating; Headache; Hoarseness ; Joint pain ; Large bones of the face; Large feet; Large hands; Large glands in the skin (sebaceous glands); Large jaw (prognathism) and tongue; Limited joint movement; Sleep apnea ; Swelling of the bony areas around a joint; Thickening of the skin, skin tags; Widely spaced teet
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acromegaly - Conventional Treatments
(Source: MedLinePlus)
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Treatment Surgery to remove the pituitary tumor that is causing this condition usually corrects the abnormal growth hormone release in most patients. Sometimes the tumor is too large to remove completely. People who do not respond to surgery will have radiation of the pituitary gland. However, the reduction in growth hormone levels after radiation is very slow. The following medications may be used to treat acromegaly: Octreotide (Sandostatin) or bromocriptine (Parlodel) may control growth horm
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Further Reading on acromegaly
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Brain Cancer - Treatment Option Overview (
WebMD
)
The goals of treatment of pituitary adenomas include normalization of hormonal secretion ( i . e ., normalization of hypersecretion and ...responsive to medical therapy.[6] Treatment for acromegaly includes...
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Phosphate in Blood (
WebMD
)
A phosphate test measures the amount of the mineral phosphate in a blood sample . The body needs ...Kidney disease, underactive parathyroid glands (hypoparathyroidism), acromegaly , rhabdomyolysis,
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Oral Glucose Tolerance Test (
WebMD
)
The oral glucose tolerance test ( OGTT ) measures the body ' s ability to use a type of sugar , called glucose , that is the body ' s main ...Overproduction of growth hormone ( acromegaly ). Pheochromocytoma.
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Blood Glucose (
WebMD
)
A blood glucose test measures the amount of a type of sugar , called glucose , in your blood . Glucose ...such as corticosteroids, or excess production of growth hormone ( acromegaly ). Low values A fasting...
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Creatinine and Creatinine Clearance (
WebMD
)
Creatinine and creatinine clearance tests measure the level of the waste product creatinine in your ...or muscle conditions (such as rhabdomyolysis, gigantism, acromegaly , myasthenia gravis, muscular...
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Growth Hormone (
WebMD
)
A growth hormone ( GH ) test measures the amount of human growth hormone ( GH ) in the blood . GH is produced by the pituitary gland ...and feet to grow larger than normal ( acromegaly ). Growth hormone can...
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Acromegaly FAQs (
eMedicineHealth
)
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